Dissecting the Genetic Basis of Sex and Dioecy in Cannabis Sativa (2021)

Nolan Kane, PhD

Associate Professor, Ecology and Evolutionary Biology, University of Colorado Boulder

As hemp continues to become an ever more economically valuable/important crop, it becomes increasingly necessary to understand the mechanism of sex determination. Understanding these processes will help to develop new approaches, tools, and pipelines, which will propel Cannabis into the modern era as […]

Investigating the Effect of Cannabidiol and Cannabidiol-trazodone Combination Treatment on Naturally Occurring Canine Cognitive Dysfunction Syndrome as a Surrogate for Alzheimer’s Disease (2021)

Stephanie McGrath, PhD
Associate Professor, Neurology, Colorado State University

The World Health Organization predicts that Alzheimer’s disease (AD) and other dementias will be the second leading cause of death in the United States within the next decade. Unfortunately, multimodal treatment efforts, with drugs, vaccines, and stem cell therapies, have yet to be successful. Neurodegenerative disorders are […]

Quantification of Endo- and Phytocannabinoids with Comparison to Pain Medication Requirements and Surgical Outcomes for Patients Undergoing Abdominal Surgery for Cancer (2021)

Camille Stewart, MD
Assistant Professor of Surgery, Division of Surgical Oncology, University of Colorado Anschutz Medical Campus

The use of cannabis is expanding in the United States. There is, however, a critical lacking in our understanding of how cannabis and its associated chemical compounds, called cannabinoids, affect patients after surgery. Patients undergoing abdominal surgery have substantial […]

Exploring Intoxication During Acute Alcohol and Cannabis Co-Administration: A Focus on Cannabinoid Content and Order Effects (2021)

Hollis Karoly, PhD
Assistant Professor, Department of Psychology, Colorado State University

Cannabis is the most commonly used drug among people who drink alcohol, yet evidence on the effects of using these substances together is quite limited. Two important factors that might impact the relationship between cannabis and alcohol use are the specific type of cannabis used […]

Defining the Effects of CBD Consumption During Pregnancy on Fetal Neurodevelopment and Postnatal Anxiety (2021)

Emily Bates, PhD
Associate Professor, Pediatrics-Developmental Biology, University of Colorado Anschutz Medical Campus

Morning sickness during pregnancy can be debilitating for a significant portion of women. Because there are not good remedies easily available and marijuana can help with nausea, women are drawn to using it, or the non-psychoactive component cannabidiol (CBD), thinking it is safe […]

Is What You See What You Get? A Systematic, Public Health-driven Analysis of Cannabis Product Label Claims VS. Actual Cannabinoid Content (2021)

Cinnamon Bidwell, PhD
Institute of Cognitive Science Faculty, Assistant Professor, University of Colorado Boulder

Duncan Mackie, PhD
Director of Pharmacology & Experimental Therapeutics, MedPharm Holdings

This project constitutes an independent and comprehensive evaluation of cannabis product label claims and testing infrastructure in the State of Colorado. The primary aim is to determine the actual cannabinoid potency (via […]

Cannabinoid Conversion to CBN During Hemp Extraction and Post-Extraction Fluorination of CBD and CBN for Increased Bioavailability (2021)

Ken Olejar, PhD
Colorado State University Pueblo

Large numbers of therapies originate from compounds originating in plants. Cannabinoids produced by industrial hemp are a group of compounds that are emerging for potential medical use. One problem that exists with all-natural compounds is their bioavailability. Studies have shown that when many of these compounds are given at therapeutic […]

Short-term Effects of Cannabis use and Cannabinoids in Youth: A Sibling-Comparison Study (2021)

Jarrod Ellingson, PhD
Assistant Professor, Psychiatry-Substance Dependence, University of Colorado School of Medicine

In the last 10 years, cannabis has become more accessible and more potent in tetrahydrocannabinol [THC] content. Prior studies have linked earlier cannabis use and greater THC potency to adverse mental health outcomes. However, these studies generally suffer from two important limitations. First, […]

Microbiome-Mediated Effects of Cannabis and CBD on Neurotransmitter-Related Molecular Networks and Anxiety (2021)

Nichole Reisdorph, PhD
Professor Mass Spectrometry Facility Director, Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus

Orally consumed Cannabis and extracted cannabidiol (CBD) products are becoming widely used supplements for a range of health disorders, including depression and anxiety. However, there is limited understanding regarding how Cannabis and CBD affect those living with these […]