Quantification of Endo- and Phytocannabinoids with Comparison to Pain Medication Requirements and Surgical Outcomes for Patients Undergoing Abdominal Surgery for Cancer (2021)

Camille Stewart, MD
Assistant Professor of Surgery, Division of Surgical Oncology, University of Colorado Anschutz Medical Campus

The use of cannabis is expanding in the United States. There is, however, a critical lacking in our understanding of how cannabis and its associated chemical compounds, called cannabinoids, affect patients after surgery. Patients undergoing abdominal surgery have substantial pain after surgery and often experience complications. Since we have found that cannabis is of interest to surgical patients diagnosed with cancer, they represent an ideal population to study. In our planned research, we will measure blood cannabinoid levels in daily cannabis users and non-users who undergo abdominal surgery for the treatment of cancer. Pain levels, pain medication requirements, and post-surgery complications will also be assessed. We think that patients with higher blood levels of cannabinoids will have more pain and need more pain medication after surgery, but that they will have similar rates of post-surgery complications. The information gained from this research will help doctors and patients understand how cannabis use affects patients after surgery and help determine if cannabis use is safe to use around the time of surgery.

More Continuing Research

Dissecting the Genetic Basis of Sex and Dioecy in Cannabis Sativa (2021)

Nolan Kane, PhD

Associate Professor, Ecology and Evolutionary Biology, University of Colorado Boulder

As hemp continues to become an ever more economically valuable/important crop, it becomes increasingly necessary to understand the mechanism of sex determination. Understanding these processes will help to develop new approaches, tools, and pipelines, which will propel Cannabis into the modern era as […]

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Investigating the Effect of Cannabidiol and Cannabidiol-trazodone Combination Treatment on Naturally Occurring Canine Cognitive Dysfunction Syndrome as a Surrogate for Alzheimer’s Disease (2021)

Stephanie McGrath, PhD
Associate Professor, Neurology, Colorado State University

The World Health Organization predicts that Alzheimer’s disease (AD) and other dementias will be the second leading cause of death in the United States within the next decade. Unfortunately, multimodal treatment efforts, with drugs, vaccines, and stem cell therapies, have yet to be successful. Neurodegenerative disorders are […]

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Quantification of Endo- and Phytocannabinoids with Comparison to Pain Medication Requirements and Surgical Outcomes for Patients Undergoing Abdominal Surgery for Cancer (2021)

Camille Stewart, MD
Assistant Professor of Surgery, Division of Surgical Oncology, University of Colorado Anschutz Medical Campus

The use of cannabis is expanding in the United States. There is, however, a critical lacking in our understanding of how cannabis and its associated chemical compounds, called cannabinoids, affect patients after surgery. Patients undergoing abdominal surgery have substantial […]

Read More »

Exploring Intoxication During Acute Alcohol and Cannabis Co-Administration: A Focus on Cannabinoid Content and Order Effects (2021)

Hollis Karoly, PhD
Assistant Professor, Department of Psychology, Colorado State University

Cannabis is the most commonly used drug among people who drink alcohol, yet evidence on the effects of using these substances together is quite limited. Two important factors that might impact the relationship between cannabis and alcohol use are the specific type of cannabis used […]

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Defining the Effects of CBD Consumption During Pregnancy on Fetal Neurodevelopment and Postnatal Anxiety (2021)

Emily Bates, PhD
Associate Professor, Pediatrics-Developmental Biology, University of Colorado Anschutz Medical Campus

Morning sickness during pregnancy can be debilitating for a significant portion of women. Because there are not good remedies easily available and marijuana can help with nausea, women are drawn to using it, or the non-psychoactive component cannabidiol (CBD), thinking it is safe […]

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