ICR State FY24

Endocannabinoids in Children with Autism Spectrum Disorder and Changes with Cannabidiol (CBD) treatment (2023)

Nicole Tartaglia, MD
Professor, Pediatrics-Developmental Pediatrics University of Colorado Anschutz Medical Campus

Children with autism often struggle with behavioral challenges including irritability, anxiety, attention deficits, aggressive behaviors or self-injurious behaviors. Endocannabinoids are naturally occurring substances in the human body that bind to cannabinoid receptors and have actions across the body including significant effects on […]

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Examination of the bi-directional interactions between phytocannabinoids and a human-associated gut microbiota (2023)

Jessica Prenni, PhD, and Tiffany Weir, PhD
Associate Professor, Department of Horticulture and Landscape Architecture (JP), and Professor, Food Science and Human Nutrition (TW), Colorado State University

In recent decades, the gut microbiome has emerged as a critical regulator of inflammation and immunity in humans and has been associated with the development of numerous chronic […]

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Investigation of polycyclic aromatic hydrocarbons resulting from vaped or dabbed cannabis/cannabis-derived products with known adverse health effects (2023)

Alison Bauer, PhD
Associate Professor, Department of Environmental & Occupational Health, University of Colorado Anschutz Medical Campus

According to the 2021 Health Kids Survey (CDPHE), among kids who use cannabis in Colorado, ~16% vape and ~22% dab cannabis. Cannabis vaping and electronic dabbing could lead to emissions of toxicants that are currently not tested, that are […]

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Developing predictive models to distinguish alcohol use, cannabis use and co-use: an exploration of electroenceph-alography (EEG) metrics and traditional intoxication measures (2023)

Hollis Karoly, PhD and Patti Davies, PhD
Assistant Professor, Department of Psychology (HK), and Professor, Department of Occupational Therapy (PD), Colorado State University

Alcohol and cannabis are commonly used at the same time and are both known to impair cognitive and psychomotor functions relevant for driving. Following legalization of recreational cannabis in Colorado, DUIs involving cannabis […]

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Increasing the Analytical Testing Capability of Cannabinoids and Concomitant Phytomolecules in Cannabis-derived Plant Matrices (2023)

William Baurerle, PhD
Professor, Department of Horticulture and Landscape Architecture, Colorado State University

Water for irrigation and essential elements for plant nutrition, two critical inputs for Cannabis production, are finite resources. We aim to quantify Cannabis crop essential element and water use requirements in intensive horticulture production systems. Quantitative data of this nature provides mineral nutrient […]

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Identifying the neuronal cell-types responsible for the rewarding and aversive properties of THC (2023)

David Root, PhD
Assistant Professor, Department of Psychology and Neuroscience, University of Colorado Boulder

Marijuana is among the most widely used psychoactive substances across the world. The active ingredient in marijuana, Δ9-tetrahydrocannabinol (THC), has rewarding qualities and some individuals will become addicted to using it. THC has aversive properties as well at higher doses. On the […]

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