ICR State FY20

In FY20, the ICR supported 15 research projects across the disciplines of biology, chemistry, agronomy, physiology, psychology, marketing, engineering, and computer information science. Funded projects included several multi-year projects, and projects that seek to develop partnerships with individuals and institutions outside of Colorado State University Pueblo such as the University of Nebraska-Lincoln, Dr. Libby Stuyt, Dr. Eun Soo Kim, and Dr. Kyungho Lee.

Interactions of Penicillium Spinulosum with Hemo and Nonpsychoactive Hemp Compounds (2020)

Dr. Sandra Bonetti, Chemistry

In nature, fungi and plants have developed close ecological relationships due to their co-evolution on earth. The interactions between fungi and plants are diverse and may be beneficial or detrimental depending on environmental conditions and the organisms involved. Mycorrhizal fungi are symbiotically associated plant host root systems, which provide enhanced water […]

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Anti-Cancer Potential of Fermented Dietary Hempseed (CANNABIS SATIVA L.) Metabolites and the Role of CB Receptors in Human Colon Cancer Cell CACO2 Viability, Proliferation, and Energy Metabolism (2020)

Dr. Annette Gabaldón, Biology

The objective of this study is to determine whether metabolites generated through probiotic fermentation of dietary hempseed (Cannabis sativa L.) exert anti-cancer effects. Specifically, we will culture human colorectal carcinoma cells Caco-2 in growth media supplemented with hempseed fermentation supernatant and test for alterations in cell viability, proliferation, and energy metabolism.

Previously, […]

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Sexually Dimorphic Effects of Cannabinoids on Cognitive and Reflexive Learning and Memory-Dependent Neuronal Network Activity in Mouse Hippocampus and Amygdala (2020)

Dr. Jeff Smith, Biology

The broad objectives of this proposed research are to quantitatively identify the degree to which electrical activity in specific neuronal populations that support fear learning and memory in the mammalian brain is targeted in a sexually dimorphic way by the cannabinoids; Dexanabinol, a synthetic cannabinoid used in human clinical trials for […]

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Data Analytics in Cannabis Research (2020)

Dr. Kuang-Yuan Huang, CIS

There are two goals of the proposed research. First, we will continue our ICR-funded research on analyzing the big data collected from a large cannabis online support forum. Specifically, the goal is to analyze the social network data constructed from the social interaction history among cannabis quitters in the online support […]

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Cannabis Use Survey Instrument Development and Implementation (2020)

Dr. Karen Yescavage, Psychology

The objective of this project is to engage in survey instrument development, assessing its psychometric properties, in order to build an empirical cannabis knowledge base. Once survey is both reliable and valid, objective is to research the reasons why people use and how they use cannabis, both medicinally and recreationally. Specific […]

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Applications of Industrial Hemp (Multi-Year Project) (2020)

Dr. Brian Vanden Heuvel, Biology

This project enables an inter-departmental, multi-faculty collaborative workflow that builds on 18 months of previous achievements by the principal investigator and co-principal investigators and established infrastructure through previous ICR funding. We believe that it is time to extend our work to applied projects.

Specifically, this proposal asks: 1) Can industrial hemp be […]

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Rheological characteristics of hemp-based filament composites for 3D printing (Multi-Year Project) (2020)

Dr. Neb Jaksic, Engineering 

This research investigates flow characteristics of various hemp-based composites used in 3D printing. It is an expansion to the research already in progress. While the current research is based on the goal of optimizing the hemp-plastic ratio in filament composites, this proposed research emphasizes understanding of underlying principles and it should further help […]

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An ongoing investigation into the effects of medicinal cannabis on seizures in adults with medically refractory epilepsy (Multi-Year Project) (2020)

Dr. Barbara Brett-Green, Psychology

The primary objective for this project is to continue an ongoing study into the effects of medicinal cannabis on seizures in adults with medically refractory epilepsy. The Principal Investigator has established a partnership with Realm of Caring, a nonprofit organization, to provide support services for patients, and iC42, a bioanalytics company, to […]

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